<?xml version="1.0" encoding="UTF-8"?>

<CodeSystem xmlns="http://hl7.org/fhir">
  <id value="certainty-type"/>
  <meta>
    <lastUpdated value="2023-03-26T15:21:02.749+11:00"/>
    <profile value="http://hl7.org/fhir/StructureDefinition/shareablecodesystem"/>
  </meta>
  <text>
    <status value="generated"/>
    <div xmlns="http://www.w3.org/1999/xhtml">
      <p>This code system 
        <code>http://hl7.org/fhir/certainty-type</code> defines the following codes:
      </p>
      <table class="codes">
        <tr>
          <td style="white-space:nowrap">
            <b>Code</b>
          </td>
          <td>
            <b>Display</b>
          </td>
          <td>
            <b>Definition</b>
          </td>
        </tr>
        <tr>
          <td style="white-space:nowrap">Overall
            <a name="certainty-type-Overall"> </a>
          </td>
          <td>Overall certainty</td>
          <td>Overall certainty of evidence (quality of evidence).</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">RiskOfBias
            <a name="certainty-type-RiskOfBias"> </a>
          </td>
          <td>Risk of bias</td>
          <td>methodologic concerns reducing internal validity.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">Inconsistency
            <a name="certainty-type-Inconsistency"> </a>
          </td>
          <td>Inconsistency</td>
          <td>concerns that findings are not similar enough to support certainty.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">Indirectness
            <a name="certainty-type-Indirectness"> </a>
          </td>
          <td>Indirectness</td>
          <td>concerns reducing external validity.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">Imprecision
            <a name="certainty-type-Imprecision"> </a>
          </td>
          <td>Imprecision</td>
          <td>fuzzy or wide variability.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">PublicationBias
            <a name="certainty-type-PublicationBias"> </a>
          </td>
          <td>Publication bias</td>
          <td>likelihood that what is published misrepresents what is available to publish.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">DoseResponseGradient
            <a name="certainty-type-DoseResponseGradient"> </a>
          </td>
          <td>Dose response gradient</td>
          <td>higher certainty due to dose response relationship.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">PlausibleConfounding
            <a name="certainty-type-PlausibleConfounding"> </a>
          </td>
          <td>Plausible confounding</td>
          <td>higher certainty due to risk of bias in opposite direction.</td>
        </tr>
        <tr>
          <td style="white-space:nowrap">LargeEffect
            <a name="certainty-type-LargeEffect"> </a>
          </td>
          <td>Large effect</td>
          <td>higher certainty due to large effect size.</td>
        </tr>
      </table>
    </div>
  </text>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-wg">
    <valueCode value="cds"/>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-standards-status">
    <valueCode value="trial-use"/>
  </extension>
  <extension url="http://hl7.org/fhir/StructureDefinition/structuredefinition-fmm">
    <valueInteger value="1"/>
  </extension>
  <url value="http://hl7.org/fhir/certainty-type"/>
  <identifier>
    <system value="urn:ietf:rfc:3986"/>
    <value value="urn:oid:2.16.840.1.113883.4.642.4.1939"/>
  </identifier>
  <version value="5.0.0"/>
  <name value="EvidenceCertaintyType"/>
  <title value="Evidence Certainty Type"/>
  <status value="active"/>
  <experimental value="false"/>
  <date value="2020-12-28T16:55:11+11:00"/>
  <publisher value="HL7 (FHIR Project)"/>
  <contact>
    <telecom>
      <system value="url"/>
      <value value="http://hl7.org/fhir"/>
    </telecom>
    <telecom>
      <system value="email"/>
      <value value="fhir@lists.hl7.org"/>
    </telecom>
  </contact>
  <description value="The aspect of quality, confidence, or certainty."/>
  <jurisdiction>
    <coding>
      <system value="http://unstats.un.org/unsd/methods/m49/m49.htm"/>
      <code value="001"/>
      <display value="World"/>
    </coding>
  </jurisdiction>
  <caseSensitive value="true"/>
  <valueSet value="http://hl7.org/fhir/ValueSet/certainty-type"/>
  <content value="complete"/>
  <concept>
    <code value="Overall"/>
    <display value="Overall certainty"/>
    <definition value="Overall certainty of evidence (quality of evidence)."/>
  </concept>
  <concept>
    <code value="RiskOfBias"/>
    <display value="Risk of bias"/>
    <definition value="methodologic concerns reducing internal validity."/>
  </concept>
  <concept>
    <code value="Inconsistency"/>
    <display value="Inconsistency"/>
    <definition value="concerns that findings are not similar enough to support certainty."/>
  </concept>
  <concept>
    <code value="Indirectness"/>
    <display value="Indirectness"/>
    <definition value="concerns reducing external validity."/>
  </concept>
  <concept>
    <code value="Imprecision"/>
    <display value="Imprecision"/>
    <definition value="fuzzy or wide variability."/>
  </concept>
  <concept>
    <code value="PublicationBias"/>
    <display value="Publication bias"/>
    <definition value="likelihood that what is published misrepresents what is available to publish."/>
  </concept>
  <concept>
    <code value="DoseResponseGradient"/>
    <display value="Dose response gradient"/>
    <definition value="higher certainty due to dose response relationship."/>
  </concept>
  <concept>
    <code value="PlausibleConfounding"/>
    <display value="Plausible confounding"/>
    <definition value="higher certainty due to risk of bias in opposite direction."/>
  </concept>
  <concept>
    <code value="LargeEffect"/>
    <display value="Large effect"/>
    <definition value="higher certainty due to large effect size."/>
  </concept>
</CodeSystem>