| Name | Flags | Card. | Type | Description & Constraints |
|---|---|---|---|---|
| TU | DomainResource | Representation of a molecular sequence Elements defined in Ancestors: id, meta, implicitRules, language, text, contained, extension, modifierExtension | ||
| Σ | 0..* | Identifier | Unique ID for this particular sequence | |
| Σ | 0..1 | code | aa | dna | rna Binding: sequence Type (Required) | |
| Σ | 0..1 | Reference(Patient | Group | Substance | BiologicallyDerivedProduct | NutritionProduct) | Subject this sequence is associated too | |
| Σ | 0..* | Reference(Any) | What the molecular sequence is about, when it is not about the subject of record | |
| Σ | 0..1 | Reference(Specimen) | Specimen used for sequencing | |
| Σ | 0..1 | Reference(Device) | The method for sequencing | |
| Σ | 0..1 | Reference(Organization) | Who should be responsible for test result | |
| Σ | 0..1 | string | Sequence that was observed | |
| Σ | 0..* | Attachment | Embedded file or a link (URL) which contains content to represent the sequence | |
| Σ | 0..* | BackboneElement | A sequence defined relative to another sequence | |
| Σ | 1..1 | CodeableConcept | Ways of identifying nucleotides or amino acids within a sequence Binding: LL5323-2 (Extensible) | |
| 0..1 | integer | Indicates the order in which the sequence should be considered when putting multiple 'relative' elements together | ||
| 0..1 | Range | Indicates the nucleotide range in the composed sequence when multiple 'relative' elements are used together | ||
| ΣC | 0..1 | BackboneElement | A sequence used as starting sequence + Rule: Both genomeAssembly and chromosome must be both contained if either one of them is contained + Rule: Have and only have one of the following elements in startingSequence: 1. genomeAssembly; 2 sequence | |
| ΣC | 0..1 | CodeableConcept | The genome assembly used for starting sequence, e.g. GRCh38 Binding: LL1040-6 (Extensible) | |
| ΣC | 0..1 | CodeableConcept | Chromosome Identifier Binding: LL2938-0 (Required) | |
| ΣC | 0..1 | The reference sequence that represents the starting sequence Binding: Multiple bindings acceptable (NCBI or LRG) (Example) | ||
| CodeableConcept | ||||
| string | ||||
| Reference(MolecularSequence) | ||||
| Σ | 0..1 | integer | Start position of the window on the starting sequence | |
| Σ | 0..1 | integer | End position of the window on the starting sequence | |
| Σ | 0..1 | code | sense | antisense Binding: orientation Type (Required) | |
| Σ | 0..1 | code | watson | crick Binding: strand Type (Required) | |
| Σ | 0..* | BackboneElement | Changes in sequence from the starting sequence | |
| Σ | 0..1 | integer | Start position of the edit on the starting sequence | |
| Σ | 0..1 | integer | End position of the edit on the starting sequence | |
| Σ | 0..1 | string | Allele that was observed | |
| Σ | 0..1 | string | Allele in the starting sequence | |