{
  "types": [
    "SubstanceDefinition"
  ],
  "SubstanceDefinition": {
    "elements": {
      "SubstanceDefinition.characterization": {
        "status": "new"
      },
      "SubstanceDefinition.characterization.technique": {
        "status": "new"
      },
      "SubstanceDefinition.characterization.form": {
        "status": "new"
      },
      "SubstanceDefinition.characterization.description": {
        "status": "new"
      },
      "SubstanceDefinition.characterization.file": {
        "status": "new"
      },
      "SubstanceDefinition.referenceInformation": {
        "status": "new"
      },
      "SubstanceDefinition.name.language": {
        "binding-strength-changed": true,
        "binding-valueset-changed": true,
        "max-valueset-changed": true,
        "binding-status": "changed",
        "old-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/languages",
          "strength": "preferred",
          "max": "http://hl7.org/fhir/ValueSet/all-languages"
        },
        "new-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/all-languages|5.0.0",
          "strength": "required"
        }
      },
      "SubstanceDefinition.nucleicAcid": {
        "status": "new"
      },
      "SubstanceDefinition.polymer": {
        "status": "new"
      },
      "SubstanceDefinition.protein": {
        "status": "new"
      },
      "SubstanceDefinition.sourceMaterial.countryOfOrigin": {
        "binding-valueset-changed": true,
        "binding-status": "changed",
        "old-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/country|4.3.0",
          "strength": "required"
        },
        "new-binding": {
          "reference": "http://hl7.org/fhir/ValueSet/country|5.0.0",
          "strength": "required"
        }
      }
    },
    "status": "changed"
  }
}